Localization of a breast cancer tumour-suppressor gene to a 3-cM interval within chromosomal region 16q22

Allelic losses on chromosome 16q in tumour cells are frequent in a variety of malignancies, suggesting the presence of one or more tumour-suppressor genes in the region. Among 210 sporadic breast cancers we examined using 15 microsatellite markers on the long arm of chromosome 16, heterozygosity for...

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Veröffentlicht in:	British journal of cancer 1997-01, Vol.75 (2), p.264-267
Hauptverfasser:	Iida, A, Isobe, R, Yoshimoto, M, Kasumi, F, Nakamura, Y, Emi, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomedical and Life Sciences Biomedicine Breast Neoplasms - genetics Cancer Research Carcinoma, Ductal, Breast - genetics Chromosome Mapping Chromosomes, Human, Pair 16 Drug Resistance Epidemiology experimental-oncology Female Genes, Tumor Suppressor Gynecology. Andrology. Obstetrics Heterozygote Humans Mammary gland diseases Medical sciences Microsatellite Repeats Molecular Medicine Oncology Sequence Deletion Tumors
Online-Zugang:	Volltext
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