The relative significance of spinal and supraspinal actions in the antinociceptive effect of morphine in the dorsal horn: an evaluation of the microinjection technique

1 Large quantities of morphine injected directly into the brainstem of spinal anaesthetized cats inhibited the noxious heat‐evoked excitation of dorsal horn neurones. The amounts required were similar to those that were required intravenously in cats with the spinal cord intact or transected. 2 When...

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Veröffentlicht in:British journal of pharmacology 1983-07, Vol.79 (3), p.807-818
Hauptverfasser: Clark, S.L., Edeson, R.O., Ryall, R.W.
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Sprache:eng
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