THE RESPONSE OF THE ISOLATED DUCTUS ARTERIOSUS TO TRANSMURAL STIMULATION AND DRUGS

1 Responses of isolated ductus arteriosus preparations from near term guinea‐pigs and lambs to transmural electrical stimulation and drugs were studied in a low oxygen medium (Po2 19 to 28 mmHg). 2 Acetylcholine and noradrenaline contracted both vessels in a dose‐dependent manner, their threshold be...

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Veröffentlicht in:	British journal of pharmacology 1980-01, Vol.71 (2), p.419-427
Hauptverfasser:	BODACH, E., COCEANI, F., DUMBRILLE, A., OKPAKO, D.T., OLLEY, P.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Atropine - pharmacology Bretylium Compounds - pharmacology Ductus Arteriosus - drug effects Ductus Arteriosus - physiology Electric Stimulation Female Guinea Pigs Norepinephrine - pharmacology Phentolamine - pharmacology Pregnancy Reserpine - pharmacology Sheep Species Specificity
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