Insulin induces airway smooth muscle contraction

Background and purpose: Recently, the use of inhaled insulin formulations for the treatment of type I and type II diabetes has been approved in Europe and in the United States. For regular use, it is critical that airway function remains unimpaired in response to insulin exposure. Experimental appro...

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Veröffentlicht in:	British journal of pharmacology 2007-01, Vol.150 (2), p.136-142
Hauptverfasser:	Schaafsma, D, Gosens, R, Ris, J M, Zaagsma, J, Meurs, H, Nelemans, S A
Format:	Artikel
Sprache:	eng
Schlagworte:	airway smooth muscle Animals Biological and medical sciences contraction Guinea Pigs guinea‐pig In Vitro Techniques insulin Insulin - pharmacology Insulin - physiology Male Medical sciences Muscle Contraction Muscle, Smooth - metabolism Muscle, Smooth - physiology Pharmacology. Drug treatments prostaglandins Prostaglandins - biosynthesis Research Papers Respiratory Mucosa - physiology Rho‐kinase Trachea - metabolism Trachea - physiology
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