A Genomic Screen in Yeast Reveals Novel Aspects of Nonstop mRNA Metabolism

Nonstop mRNA decay, a specific mRNA surveillance pathway, rapidly degrades transcripts that lack in-frame stop codons. The cytoplasmic exosome, a complex of 3'-5' exoribonucleases involved in RNA degradation and processing events, degrades nonstop transcripts. To further understand how non...

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Veröffentlicht in:	Genetics (Austin) 2007-10, Vol.177 (2), p.773-784
Hauptverfasser:	Wilson, Marenda A, Meaux, Stacie, van Hoof, Ambro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Codon, Terminator Exoribonucleases Gene expression Genetics Genome, Fungal Genomics Genomics - methods Inositol Phosphates Investigations Kinases Mutation Proteasome Endopeptidase Complex Proteins Ribonucleic acid RNA RNA Stability - genetics RNA, Messenger - metabolism Saccharomyces cerevisiae Proteins - physiology
Online-Zugang:	Volltext
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