Adjuvant intraoperative photodynamic therapy diminishes the rate of local recurrence in a rat mammary tumour model

The use of photodynamic therapy (PDT) as an adjunct to curative tumour resection was investigated in a tumour recurrence model, using rat mammary adenocarcinoma BN472. Tumours were inoculated subcutaneously in 60 animals and resected after 21 days of growth. Immediately after removal, the operation...

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Veröffentlicht in:	British journal of cancer 1995-04, Vol.71 (4), p.733-737
Hauptverfasser:	van Hillegersberg, R, Hekking-Weijma, JM, Wilson, JHP, Edixhoven-Bosdijk, A, Kort, WJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - enzymology Adenocarcinoma - pathology Adenocarcinoma - surgery Aminolevulinic Acid - administration & dosage Aminolevulinic Acid - therapeutic use Analysis of Variance Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Chemotherapy, Adjuvant Drug Resistance Epidemiology experimental-oncology Female Ferrochelatase - metabolism Hematoporphyrin Derivative - administration & dosage Hematoporphyrin Derivative - therapeutic use Hydroxymethylbilane Synthase - metabolism Light Lymphatic Metastasis - prevention & control Mammary Neoplasms, Experimental - drug therapy Mammary Neoplasms, Experimental - enzymology Mammary Neoplasms, Experimental - pathology Mammary Neoplasms, Experimental - surgery Medical sciences Molecular Medicine Neoplasm Recurrence, Local - prevention & control Oncology Photoradiation therapy and photosensitizing agent Porphyrins - metabolism Rats Rats, Inbred BN Treatment with physical agents Treatment. General aspects Tumors
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