Oral administration of Ginkgo biloba extract, EGb‐761 inhibits thermal hyperalgesia in rodent models of inflammatory and post‐surgical pain

Background and purpose: Studies in vitro suggest that the standardised extract of Ginkgo biloba, EGb‐761 has anti‐inflammatory properties and modulatory effects on key pain‐related molecules. This study investigated the analgesic and anti‐inflammatory effects of EGb‐761 on carrageenan‐induced inflam...

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Veröffentlicht in:	British journal of pharmacology 2007-05, Vol.151 (2), p.285-291
Hauptverfasser:	Biddlestone, L, Corbett, A D, Dolan, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral analgesia Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Carrageenan - administration & dosage Carrageenan - toxicity Diclofenac - administration & dosage Diclofenac - pharmacology Disease Models, Animal Dose-Response Relationship, Drug Ginkgo biloba Hindlimb - drug effects Hindlimb - pathology Hindlimb - physiopathology Hyperalgesia - chemically induced Hyperalgesia - physiopathology Hyperalgesia - prevention & control inflammation Inflammation - complications Injections, Intradermal Male mechanical allodynia Medical sciences Pain - etiology Pain - physiopathology Pain - prevention & control Pain Measurement - methods Pain, Postoperative - physiopathology Pain, Postoperative - prevention & control Pharmacology. Drug treatments Plant Extracts - administration & dosage Plant Extracts - pharmacology post‐surgical pain Rats Rats, Wistar Research Papers thermal hyperalgesia
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