5‐HT4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice

Background and purpose: A strategy to treat Alzheimer's disease (AD) is to increase the soluble form of amyloid precursor protein (sAPPα), a promnesic protein, in the brain. Because strong evidence supports beneficial effects of 5‐hydroxytryptamine 5‐HT4 receptor agonists in memory and learning...

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Veröffentlicht in:	British journal of pharmacology 2007-04, Vol.150 (7), p.883-892
Hauptverfasser:	Cachard‐Chastel, M, Lezoualc'h, F, Dewachter, I, Deloménie, C, Croes, S, Devijver, H, Langlois, M, Leuven, F, Sicsic, S, Gardier, A M
Format:	Artikel
Sprache:	eng
Schlagworte:	5‐HT4 receptor agonist acetylcholinesterase inhibitor Adult and adolescent clinical studies Alzheimer's disease amyloid precursor protein Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Medical sciences Neurology Organic mental disorders. Neuropsychology Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Research Papers
Online-Zugang:	Volltext
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