In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor?

Background and purpose: The CB2 receptor has been proposed as a novel target for the treatment of pain, and CB2 receptor agonists defined in in vitro assays have demonstrated analgesic activity in animal models. Based on its in vivo analgesic efficacy, AM1241 has been classified as a CB2‐selective a...

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Veröffentlicht in:	British journal of pharmacology 2006-09, Vol.149 (2), p.145-154
Hauptverfasser:	Yao, B B, Mukherjee, S, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Hooker, B A, Dart, M J, Sullivan, J P, Meyer, M D
Format:	Artikel
Sprache:	eng
Schlagworte:	AM1241 Biological and medical sciences cannabinoid Cannabinoids - pharmacology CB2 receptor Cell Line GPCR Humans Medical sciences Pharmacology. Drug treatments protean agonist receptor constitutive activity Receptor, Cannabinoid, CB2 - agonists Research Papers
Online-Zugang:	Volltext
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