Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study

Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) for longevity-related traits in a community-based sample. We report on 5 longevity and aging traits i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	BMC medical genetics 2007-09, Vol.8 Suppl 1 (S1), p.S13-S13, Article S13
Hauptverfasser:	Lunetta, Kathryn L, D'Agostino, Sr, Ralph B, Karasik, David, Benjamin, Emelia J, Guo, Chao-Yu, Govindaraju, Raju, Kiel, Douglas P, Kelly-Hayes, Margaret, Massaro, Joseph M, Pencina, Michael J, Seshadri, Sudha, Murabito, Joanne M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cardiovascular Diseases - genetics Cardiovascular Diseases - physiopathology Cohort Studies Female Genetic Linkage Genetic Markers Genome, Human Genotype Humans Longevity - genetics Male Middle Aged Phenotype Polymorphism, Single Nucleotide
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!