Direct involvement of the isotype-specific C-terminus of beta tubulin in ciliary beating

In previous studies in Drosophila, Nielsen et al. hypothesized that the beta tubulin C-terminal axonemal motif ;EGEFXXX', where X is an acidic amino acid, is required for ciliary function and assembly (Nielsen et al., 2001, Curr. Biol. 11, 529-533). This motif is present in some but not all mam...

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Veröffentlicht in:	Journal of cell science 2005-10, Vol.118 (Pt 19), p.4333-4341
Hauptverfasser:	Vent, Julia, Wyatt, Todd A, Smith, D David, Banerjee, Asok, Ludueña, Richard F, Sisson, Joseph H, Hallworth, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies - metabolism Cattle Cilia - metabolism Cilia - ultrastructure Epitopes Microtubules - metabolism Molecular Sequence Data Peptides - genetics Peptides - metabolism Protein Isoforms - chemistry Protein Isoforms - genetics Protein Isoforms - metabolism Protein Structure, Secondary Respiratory Mucosa - cytology Tubulin - chemistry Tubulin - genetics Tubulin - metabolism
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