The 5T mouse multiple myeloma model: absence of c-myc oncogene rearrangement in early transplant generations

Consistent chromosomal translocations involving the c-myc cellular oncogene and one of the three immunoglobin loci are typical for human Burkitt's lymphoma, induced mouse plasmacytoma (MPC) and spontaneously arising rat immunocytoma (RIC). Another plasma cell malignancy, multiple myeloma (MM),...

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Veröffentlicht in:	British journal of cancer 1990-02, Vol.61 (2), p.276-278
Hauptverfasser:	Radl, J, Punt, YA, van den Enden-Vieveen, MH, Bentvelzen, PA, Bakkus, MH, van den Akker, TW, Benner, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoradiography Biological and medical sciences Biomedical and Life Sciences Biomedicine Bone Marrow - ultrastructure Cancer Research Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Chromosome Mapping DNA, Neoplasm - analysis Drug Resistance Epidemiology experimental-oncology Female Fundamental and applied biological sciences. Psychology Gene Rearrangement Male Mice Mice, Inbred C57BL Molecular and cellular biology Molecular Medicine Multiple Myeloma - genetics Neoplasm Transplantation Oncogenes Oncology Spleen - ultrastructure
Online-Zugang:	Volltext
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