Immunohistochemical detection of mutant p53 protein in epithelial ovarian cancer using polyclonal antibody CMI: correlation with histopathology and clinical features

Approximately 30-50% of cases of ovarian adenocarcinoma harbour mutations in the p53 tumour-suppressor gene associated with elevated levels of the protein detected by immunohistochemical staining. To investigate any relation between the presence of mutant p53 and clinicopathological features of dise...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of cancer 1994-03, Vol.69 (3), p.609-612
Hauptverfasser:	RENNINSON, J, BAKER, B. W, MCGOWN, A. T, MURPHY, D, NORTON, J. D, FOX, B. W, CROWTHER, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Codon DNA Primers DNA, Neoplasm - analysis Exons Female Female genital diseases Genes, p53 Gynecology. Andrology. Obstetrics Humans Immunohistochemistry - methods Medical sciences Molecular Sequence Data Neoplasm Staging Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Point Mutation Polymerase Chain Reaction Tumor Suppressor Protein p53 - analysis Tumor Suppressor Protein p53 - genetics Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!