pH in human tumour xenografts: effect of intravenous administration of glucose

pH frequency distributions of tumours grown s.c. from 30 human tumour xenograft lines in rnu/rnu rats were analysed with the use of H+ ion-sensitive semi-microelectrodes prior to and following stimulation of tumour cell glycolysis by i.v. infusion of glucose. At normoglycemia, the average pH of the...

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Veröffentlicht in:	British journal of cancer 1993-09, Vol.68 (3), p.492-500
Hauptverfasser:	Volk, T, Jähde, E, Fortmeyer, HP, Glüsenkamp, K-H, Rajewsky, MF
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Breast Neoplasms - metabolism Cancer Research Drug Resistance Epidemiology experimental-oncology Female Gastrointestinal Neoplasms - metabolism Glucose - administration & dosage Glucose - pharmacology Humans Hydrogen-Ion Concentration Hyperglycemia - metabolism Injections, Intravenous Lung Neoplasms - metabolism Male Mannitol - pharmacology Molecular Medicine Neoplasm Transplantation Neoplasms - metabolism Neoplasms - pathology Oncology Rats Rats, Inbred Strains Sarcoma - metabolism Time Factors Transplantation, Heterologous Tumor Cells, Cultured
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