Deficiency of invariant natural killer T cells in coeliac disease

Background: Immunoregulatory invariant natural killer (iNK) T cells rapidly produce interleukin (IL)-4 and other cytokines that suppress a Th1 response and are deficient in some autoimmune diseases. Aim: The aim of this study was to investigate any deficiency of iNK T cells in coeliac disease. Metho...

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Veröffentlicht in:	Gut 2007-06, Vol.56 (6), p.790-795
Hauptverfasser:	Grose, R H, Cummins, A G, Thompson, F M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens Antigens, Differentiation, B-Lymphocyte - analysis Antigens, Differentiation, B-Lymphocyte - genetics Autoimmune diseases Biological and medical sciences Celiac disease Celiac Disease - immunology Cells, Cultured Cloning coeliac disease Diabetes Disease Duodenum - immunology Gastroenterology Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Gluten Hepatology Histocompatibility Antigens Class II - analysis Histocompatibility Antigens Class II - genetics Humans IFN Immunology Immunomodulators iNK T cell interferon interleukin Interleukin-4 - biosynthesis invariant natural killer T cell Killer Cells, Natural - immunology Lymphocyte Count Lymphocytes Medical sciences Middle Aged NK T cells Other diseases. Semiology Pathogenesis Pharmacology. Drug treatments RNA, Messenger - genetics Small Intestine Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Studies T cell receptors T-Lymphocyte Subsets - immunology α-galactosylceramide αGalCer
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