Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans

MicroRNAs (miRNAs) are regulatory molecules that share both biosynthetic derivation (cleavage from short hairpin precursor RNAs) and functional roles (downregulation of specific mRNAs through targeted degradation and/or translational inhibition). A distinct family of small RNAs, termed siRNAs, have...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	RNA (Cambridge) 2007-09, Vol.13 (9), p.1492-1504
Hauptverfasser:	Gu, Sam G, Pak, Julia, Barberan-Soler, Sergio, Ali, Mustapha, Fire, Andrew, Zahler, Alan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism MicroRNAs - analysis MicroRNAs - isolation & purification MicroRNAs - metabolism Ribonucleoproteins - metabolism RNA, Small Interfering - analysis RNA, Small Interfering - isolation & purification RNA, Small Interfering - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!