Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans

Caenorhabditis elegans is an important model for the study of DNA damage and repair related processes such as aging, neurodegeneration, and carcinogenesis. However, DNA repair is poorly characterized in this organism. We adapted a quantitative polymerase chain reaction assay to characterize repair o...

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Veröffentlicht in:	Genome Biology (Online Edition) 2007-05, Vol.8 (5), p.R70-R70, Article R70
Hauptverfasser:	Meyer, Joel N, Boyd, Windy A, Azzam, Gregory A, Haugen, Astrid C, Freedman, Jonathan H, Van Houten, Bennett
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Analysis Animals Caenorhabditis elegans Carcinogenesis DNA DNA Damage DNA repair DNA Repair - physiology Excision (Surgery) Gene expression Genes Genetic aspects Genetic research Genomes Gerontology Kinetics Physiological aspects Polymerase Chain Reaction Radiation (Physics) Roundworms Statistics Ultraviolet Rays - adverse effects
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