A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication
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Veröffentlicht in: | Journal of Virology 1997-08, Vol.71 (8), p.6100-6105 |
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container_title | Journal of Virology |
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creator | Dropulic, L K Hardwick, J M Griffin, D E |
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doi_str_mv | 10.1128/jvi.71.8.6100-6105.1997 |
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</description><subject>Animals</subject><subject>Cricetinae</subject><subject>Mice</subject><subject>RNA, Viral - biosynthesis</subject><subject>Sindbis Virus - pathogenicity</subject><subject>Sindbis Virus - physiology</subject><subject>Structure-Activity Relationship</subject><subject>Viral Envelope Proteins - chemistry</subject><subject>Viral Envelope Proteins - physiology</subject><subject>Viral Structural Proteins - biosynthesis</subject><subject>Virulence</subject><subject>Virus Replication</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAQxy0EKtvCIyDMhVuCx4kT58ChqgpFqsQBkLhZjj1JXCX2YieL9g14bBLtqqInLmNp_h-y_SPkLbAcgMsPDweX15DLvALGsnWIHJqmfkZ2wBqZCQHlc7JjjPNMFPLnS3KZ0gNjUJZVeUEuGs4Lwcod-XNNk_P9iFRPzgeqjbPUDNr3SJ2n84D0ltN-PJqwj2HGdRc6-s1527pEDy4uiZrgO4yJelxi2FYjeoO0PVI9zhjXeqo9RR3HI00z7reGUzLifnRGzy74V-RFp8eEr8_nFfnx6fb7zV12__Xzl5vr-8wIzudMgLEFb60oCyarttS8Mry2IDsLXSNAQlcUnTWFtJWsdF2VTdNUArsWa6iELa7Ix1PvfmkntAb9HPWo9tFNOh5V0E49VbwbVB8OChqQNVvz78_5GH4tmGY1uWRwHLXHsCRVN7D-rCz_a4SKi7qUYjXWJ6OJIaWI3eNlgKkNtlphqxqUVBvsbQi1wV6Tb_59y2PuTHfV3530wfXDbxdR6TQ9bSv-Av34tQ8</recordid><startdate>19970801</startdate><enddate>19970801</enddate><creator>Dropulic, L K</creator><creator>Hardwick, J M</creator><creator>Griffin, D E</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19970801</creationdate><title>A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication</title><author>Dropulic, L K ; Hardwick, J M ; Griffin, D E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-51cd32bd543086b4a26c27d18fd1f95181f33fdc38d686a76499965efbe7165d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Animals</topic><topic>Cricetinae</topic><topic>Mice</topic><topic>RNA, Viral - biosynthesis</topic><topic>Sindbis Virus - pathogenicity</topic><topic>Sindbis Virus - physiology</topic><topic>Structure-Activity Relationship</topic><topic>Viral Envelope Proteins - chemistry</topic><topic>Viral Envelope Proteins - physiology</topic><topic>Viral Structural Proteins - biosynthesis</topic><topic>Virulence</topic><topic>Virus Replication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dropulic, L K</creatorcontrib><creatorcontrib>Hardwick, J M</creatorcontrib><creatorcontrib>Griffin, D E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dropulic, L K</au><au>Hardwick, J M</au><au>Griffin, D E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication</atitle><jtitle>Journal of Virology</jtitle><addtitle>J Virol</addtitle><date>1997-08-01</date><risdate>1997</risdate><volume>71</volume><issue>8</issue><spage>6100</spage><epage>6105</epage><pages>6100-6105</pages><issn>0022-538X</issn><eissn>1098-5514</eissn><abstract>Article Usage Stats
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subjects | Animals Cricetinae Mice RNA, Viral - biosynthesis Sindbis Virus - pathogenicity Sindbis Virus - physiology Structure-Activity Relationship Viral Envelope Proteins - chemistry Viral Envelope Proteins - physiology Viral Structural Proteins - biosynthesis Virulence Virus Replication |
title | A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication |
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