Tetrasomy 15q: two marker chromosomes with no detectable alpha-satellite DNA

Two patients with specific and similar phenotypes were both found to have an unusual marker chromosome present in 70%-80% of their lymphocytes at routine cytogenetic examination. The marker chromosomes were isolated by flow sorting and were amplified by degenerate oligonucleotide-primed PCR. These l...

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Veröffentlicht in:	American journal of human genetics 1994-05, Vol.54 (5), p.877-883
Hauptverfasser:	BLENNOW, E, TELENIUS, H, DE VOS, D, LARSSON, C, HENRIKSSON, P, JOHANSSON, Ö, CARTER, N. P, NORDENSKJÖLD, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Multiple - genetics Adult ANEUPLOIDY BASIC BIOLOGICAL SCIENCES Biological and medical sciences Child, Preschool chromosome 15 Chromosome Aberrations Chromosome Mapping CHROMOSOMES Chromosomes, Human, Pair 15 CONGENITAL MALFORMATIONS DETECTION DNA HYBRIDIZATION DNA Primers DNA, Satellite - analysis Female Genetic Markers HUMAN CHROMOSOME 15 HUMAN CHROMOSOMES Humans HYBRIDIZATION In Situ Hybridization, Fluorescence Karyotyping lymphocytes Lymphocytes - pathology Male MALFORMATIONS man markers Medical genetics Medical sciences PATHOLOGICAL CHANGES Phenotype PLOIDY 550400 > Genetics Polymerase Chain Reaction repeated sequence satellite DNA tetrasomy Trisomy
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