Phentolamine and yohimbine inhibit ATP‐sensitive K+ channels in mouse pancreatic β‐cells

1 The effects of phentolamine and yohimbine on adenosine 5‐triphosphate (ATP)‐sensitive K+ channels were studied in normal mouse β‐cells. 2 In the presence of 3 mM glucose, many ATP‐sensitive K+ channels are open in the β‐cell membrane. Under these conditions, phentolamine inhibited 86Rb efflux from...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 1990-09, Vol.101 (1), p.115-120
Hauptverfasser:	Plant, T.D., Henquin, J.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - antagonists & inhibitors Adenosine Triphosphate - pharmacology Animals Biological and medical sciences Diazoxide - pharmacology Female Hormones. Endocrine system In Vitro Techniques Islets of Langerhans - drug effects Islets of Langerhans - metabolism Medical sciences Mice Pharmacology. Drug treatments Phentolamine - pharmacology Potassium Channels - drug effects Rubidium Radioisotopes Tolbutamide - pharmacology Yohimbine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!