Experimental model of ischemic bowel necrosis. The role of platelet- activating factor and endotoxin

This report deals with the experimental production of ischemic bowel necrosis in rats by the administration of combined bacterial lipopolysaccharide (LPS) and platelet-activating factor (PAF). Neither LPS alone, nor PAF at a low dose, caused ischemic intestinal necrosis when administered intraaortic...

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Veröffentlicht in:	The American journal of pathology 1983-07, Vol.112 (1), p.127-135
Hauptverfasser:	Gonzalez-Crussi, F, Hsueh, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Endotoxins Enterocolitis, Pseudomembranous - etiology Enterocolitis, Pseudomembranous - pathology Enterocolitis, Pseudomembranous - physiopathology Gastric Mucosa - pathology Ileum - pathology Intestine, Large - pathology Jejunum - pathology Male Platelet Activating Factor - physiology Platelet Aggregation Rats Rats, Inbred Strains
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