Angiotensin II receptors involved in the enhancement of noradrenergic transmission in the caudal artery of the spontaneously hypertensive rat

1 The effects of the AT1 receptor antagonist losartan and the AT2 receptor antagonist PD 123319, on actions of angiotensin II in isolated caudal arteries of spontaneously hypertensive (SH) and age‐matched normotensive (Wistar‐Kyoto) rats were compared. 2 Angiotensin II (0.1–3 μm) produced concentrat...

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Veröffentlicht in:	British journal of pharmacology 1996-11, Vol.119 (5), p.965-975
Hauptverfasser:	Cox, S.L., Story, D.F., Ziogas, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Angiotensin II - pharmacology angiotensin II receptors Angiotensin Receptor Antagonists Animals Arterial hypertension. Arterial hypotension Arteries - drug effects Arteries - physiology Biological and medical sciences Biphenyl Compounds - pharmacology Blood and lymphatic vessels Cardiology. Vascular system Experimental diseases Imidazoles - pharmacology In Vitro Techniques Losartan Medical sciences noradrenergic transmission Norepinephrine - metabolism PD 123319 Pyridines - pharmacology rat caudal artery Rats Rats, Inbred SHR Rats, Inbred WKY Receptors, Angiotensin - physiology spontaneously hypertensive rat Tetrazoles - pharmacology Vasoconstriction - drug effects
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