Evidence for 5‐HT1‐like receptor‐mediated vasoconstriction in human pulmonary artery

1 The 5‐hydroxytryptamine (5‐HT) receptors mediating contraction of human isolated pulmonary artery rings were investigated. Responses to the agonists 5‐carboximidotryptamine (5‐CT, non‐selective 5‐HT1 agonist), sumatriptan (5‐HT1D‐like receptor agonist), 5‐HT and 8‐hydroxy‐2‐(di‐n‐propylamino)‐tetr...

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Veröffentlicht in:	British journal of pharmacology 1996-09, Vol.119 (2), p.277-282
Hauptverfasser:	MacLean, Margaret R., Clayton, Robin A., Templeton, Alison G.B., Morecroft, Ian
Format:	Artikel
Sprache:	eng
Schlagworte:	5‐Hydroxytryptamine receptors 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology Benzamides - pharmacology Biological and medical sciences Blood vessels and receptors Fundamental and applied biological sciences. Psychology human pulmonary arteries Humans In Vitro Techniques Ketanserin - pharmacology Kinetics Methiothepin - pharmacology Pulmonary Artery - drug effects Pulmonary Artery - physiology Pulmonary Artery - ultrastructure Pyridines - pharmacology Receptors, Serotonin - drug effects Receptors, Serotonin - physiology Serotonin - pharmacology Serotonin Antagonists - pharmacology Serotonin Receptor Agonists - pharmacology vasoconstriction Vasoconstriction - drug effects Vasoconstriction - physiology Vertebrates: cardiovascular system
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