Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants

Results of studies to determine whether women who smoke during early pregnancy are at increased risk of delivering infants with orofacial clefts have been mixed, and recently a gene-environment interaction between maternal smoking, transforming growth factor-alpha (TGFa), and clefting has been repor...

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Veröffentlicht in:	American journal of human genetics 1996-03, Vol.58 (3), p.551-561
Hauptverfasser:	SHAW, G. M, WASSERMAN, C. R, LAMMER, E. J, O'MALLEY, C. D, MURRAY, J. C, BASART, A. M, TOLAROVA, M. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences California Case-Control Studies Cleft Lip - etiology Cleft Palate - etiology Facial bones, jaws, teeth, parodontium: diseases, semeiology Female Genetic Variation - genetics Genotype Humans Infant, Newborn Interviews as Topic Male Maternal Age Maternal Exposure Medical sciences Non tumoral diseases Otorhinolaryngology. Stomatology Paternal Exposure Polymorphism, Restriction Fragment Length Risk Factors Smoking - adverse effects Transforming Growth Factor alpha - genetics
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