Increase of extracellular brain calcium involved in interleukin‐1β‐induced pyresis in the rabbit: antagonism by dexamethasone

1 This study investigates the role of extracellular brain calcium in the hyperthermia induced by interleukin‐1β (IL‐1β). 2 Intracerebroventricular (i.c.v.) injection of IL‐1β (12.5 ng kg−1) in rabbits caused a prompt and sustained rise in cerebrospinal fluid (CSF) Ca2+ concentration ([Ca2+]) followe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 1994-06, Vol.112 (2), p.449-452
Hauptverfasser:	Palmi, M., Frosini, M., Becherucci, C., Sgaragli, G.P., Parente, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Temperature Regulation - drug effects Brain Chemistry - drug effects Brain Chemistry - physiology Calcium - cerebrospinal fluid Calcium - physiology CSF‐calcium dexamethasone Dexamethasone - administration & dosage Dexamethasone - pharmacology Dinoprostone - biosynthesis Egtazic Acid - pharmacology Extracellular Space - metabolism Extracellular Space - physiology fever Injections, Intraventricular Interleukin-1 - administration & dosage Interleukin-1 - antagonists & inhibitors Interleukin-1 - pharmacology Interleukin‐1β Male Medical sciences Miscellaneous Neuropharmacology Pharmacology. Drug treatments prostaglandin E2 Rabbits
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!