Characterization of the effects of 2‐methylthio‐ATP and 2‐chloro‐ATP on brain capillary endothelial cells: similarities to ADP and differences from ATP

1 Brain capillary endothelial cells responded to 2‐methylthio‐ATP (2MeSATP) by large increases in [Ca2+]i (EC50 = 27 nm) that were partially dependent on the presence of extracellular Ca2+ and that were not associated with a measurable production of inositol phosphates. 2 2‐chloro‐ATP (2ClATP) raise...

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Veröffentlicht in:British journal of pharmacology 1994-07, Vol.112 (3), p.775-780
Hauptverfasser: Vigne, Paul, Feolde, Erick, Breittmayer, Jean Philippe, Frelin, Christian
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Sprache:eng
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