Interaction of tolbutamide and cytosolic nucleotides in controlling the ATP‐sensitive K+ channel in mouse β‐cells

1 In mouse pancreatic β‐cells the role of cytosolic nucleotides in the regulation of the sulphonylurea sensitivity of the adenosine 5′‐triphosphate‐sensitive K+ channel (KATP‐channel) was examined. Patch‐clamp experiments with excised inside‐out membrane patches were carried out using an experimenta...

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