Pharmacological characterization of behavioural responses to SK&F 83959 in relation to ‘D1‐like’ dopamine receptors not linked to adenylyl cyclase

1 Behavioural responses to the new benzazepine derivative, SK&F 83959, a compound that both fails to stimulate adenylyl cyclase and inhibits the stimulation of adenylyl cyclase induced by dopamine, were characterized in detail. 2 In rat striatal membrane preparations, radioligand binding studies...

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Veröffentlicht in:	British journal of pharmacology 1995-10, Vol.116 (3), p.2120-2126
Hauptverfasser:	Deveney, Aaron M., Waddington, John L.
Format:	Artikel
Sprache:	eng
Schlagworte:	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - analogs & derivatives 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology adenylyl cyclase Adenylyl Cyclases - biosynthesis Adenylyl Cyclases - drug effects Animals Behavior, Animal - drug effects Benzamides - pharmacology Benzazepines - pharmacology Binding, Competitive Biological and medical sciences BW 737C Catecholaminergic system Chromans - pharmacology D1‐like Dopamine Agonists - pharmacology Dopamine Antagonists - pharmacology Dopamine D1 receptors Enzyme Induction - drug effects grooming behaviour Isoquinolines - pharmacology Male Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Radioligand Assay Rats Rats, Sprague-Dawley receptors Receptors, Dopamine D1 - drug effects SCH 23390 SK&F 83959 Spiperone - pharmacology Tetrahydroisoquinolines
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