Leukotriene receptors on human pulmonary vascular endothelium

1 Cysteinyl‐leukotrienes cause contractions and/or relaxations of human isolated pulmonary vascular preparations. Although, the localization and nature of the receptors through which these effects are mediated have not been fully characterized, some effects are indirect and not mediated via the well...

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Veröffentlicht in:	British journal of pharmacology 1995-08, Vol.115 (8), p.1382-1386
Hauptverfasser:	Ortiz, J.L., Gorenne, I., Cortijo, J., Seller, A., Labat, C., Sarria, B., Abram, T.S., Gardiner, P.J., Morcillo, E., Brink, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Arginine - analogs & derivatives Arginine - pharmacology Biological and medical sciences Blood vessels and receptors endothelium Endothelium, Vascular - chemistry Endothelium, Vascular - drug effects Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology human pulmonary vessels Humans Leukotriene D4 - pharmacology Leukotriene receptors Muscle, Smooth, Vascular - chemistry Muscle, Smooth, Vascular - drug effects nitric oxide Nitroarginine Norepinephrine - pharmacology Pulmonary Artery - drug effects Pulmonary Artery - metabolism Pulmonary Veins - chemistry Pulmonary Veins - drug effects Receptors, Leukotriene - analysis Vasoconstriction - drug effects Vasodilation - drug effects Vertebrates: cardiovascular system
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