NK2 receptors mediate plasma extravasation in guinea‐pig lower airways

1 Neurokinin (NK) receptor‐mediated extravasation has been examined in guinea‐pig airways by use of a recently described marker for microvascular protein leakage, 125I‐labelled human fibrinogen. 2 Neurokinin A (NKA) caused a dose‐dependent increase in plasma [125I]‐fibrinogen extravasation in trache...

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Veröffentlicht in:	British journal of pharmacology 1993-02, Vol.108 (2), p.383-386
Hauptverfasser:	Tousignant, Christine, Chan, Chi‐Chung, Guevremont, Diane, Brideau, Christine, Hale, Jeffrey J., MacCoss, Malcolm, Rodger, Ian W.
Format:	Artikel
Sprache:	eng
Schlagworte:	125I‐labelled human fibrinogen [β‐Ala8]NKA(4–10) Animals Benzamides - pharmacology Biological and medical sciences Blood Proteins - metabolism Bronchi - drug effects Extravasation of Diagnostic and Therapeutic Materials Guinea Pigs guinea‐pig airways Iodine Radioisotopes Male Medical sciences Miscellaneous Neurokinin A - analogs & derivatives Neurokinin A - antagonists & inhibitors Neurokinin A - pharmacology Neuropharmacology Neurotransmitters. Neurotransmission. Receptors NK2 receptor Peptide Fragments - pharmacology Pharmacology. Drug treatments Piperidines - pharmacology plasma extravasation Receptors, Neurokinin-2 Receptors, Neurotransmitter - drug effects Receptors, Neurotransmitter - physiology SR 48968
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