BK1 and BK2 bradykinin receptors in the rat duodenum smooth muscle

1 The dual action of bradykinin (relaxation and contraction) on the rat duodenum was investigated by studying its effect on adenosine 3′:5′‐cyclic monophosphate (cyclic AMP) levels in cultured duodenal smooth muscle cells, and the effects of apamin on the isolated muscle responses to agonists and an...

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Veröffentlicht in:	British journal of pharmacology 1992-12, Vol.107 (4), p.991-995
Hauptverfasser:	Feres, Teresa, Paiva, Antonio C.M., Paiva, Therezinha B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apamin Apamin - pharmacology Biological and medical sciences bradykinin Bradykinin - analogs & derivatives Bradykinin - pharmacology Cells, Cultured Cyclic AMP - metabolism Duodenum - cytology Duodenum - drug effects Duodenum - metabolism Female Fundamental and applied biological sciences. Psychology Isoproterenol - pharmacology Male Muscle Contraction - drug effects Muscle Relaxation - drug effects Muscle, Smooth - cytology Muscle, Smooth - drug effects Muscle, Smooth - metabolism potassium channels rat duodenum Rats Rats, Wistar receptors Receptors, Bradykinin Receptors, Neurotransmitter - antagonists & inhibitors Receptors, Neurotransmitter - physiology smooth muscle Stomach Vertebrates: digestive system
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