l‐Arginine dilates rat pial arterioles by nitric oxide‐dependent mechanisms and increases blood flow during focal cerebral ischaemia

l‐Arginine (≥ 30 mg kg−1, i.v.), but not d‐arginine (300 mg kg−1) administered 5 min after unilateral common carotid/middle cerebral artery occlusion increased regional cerebral blood flow (rCBF) within the dorsolateral ischaemic cortex in spontaneously hypertensive rats. l‐Arginine (300 mg kg−1) in...

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