Contribution of serotype‐specific IgG concentration, IgG subclasses and relative antibody avidity to opsonophagocytic activity against Streptococcus pneumoniae

The contribution of serotype‐specific IgG concentration, subclasses, and avidity to opsonophagocytic activity (OPA) against Streptococcus pneumoniae (Pnc) was evaluated in sera of adults and infants immunized with different pneumococcal vaccines. Antibody concentrations and avidities were measured b...

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Veröffentlicht in:	Clinical and experimental immunology 1999-12, Vol.118 (3), p.402-407
Hauptverfasser:	ANTTILA, M, VOUTILAINEN, M, JÄNTTI, V, ESKOLA, J, KÄYHTY, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Antibodies, Bacterial - blood Antibodies, Bacterial - classification Antibodies, Bacterial - immunology Antibody Specificity - immunology Applied microbiology Bacterial Capsules - immunology Bacterial Vaccines - immunology Biological and medical sciences Biological Assay conjugate vaccines Dose-Response Relationship, Immunologic Fundamental and applied biological sciences. Psychology Humans Immunoenzyme Techniques Immunoglobulin G - blood Immunoglobulin G - classification Immunoglobulin G - immunology Infant Microbiology Opsonin Proteins - immunology opsonophagocytic activity Original Phagocytosis - immunology Serotyping Streptococcus pneumoniae Streptococcus pneumoniae - immunology Streptococcuspneumoniae Time Factors Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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