Early reduction of the over‐expression of CD40L, OX40 and Fas on T cells in HIV‐1 infection during triple anti‐retroviral therapy: possible implications for lymphocyte traffic and functional recovery

Fas, CD40L and OX40 are members of the tumour necrosis factor (TNF) receptor superfamily with critical roles in T cell activation and death, B cell function, dendritic cell maturation and leucocyte traffic regulation. The aim of this study was to evaluate the effects of anti‐retroviral therapy (HAAR...

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Veröffentlicht in:	Clinical and experimental immunology 1999-05, Vol.116 (2), p.307-315
Hauptverfasser:	SOUSA, A. E, CHAVES, A. F, DOROANA, M, ANTUNES, F, VICTORINO, R. M. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - drug therapy Acquired Immunodeficiency Syndrome - immunology Acquired Immunodeficiency Syndrome - virology Adult AIDS/HIV Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents anti‐retroviral therapy Biological and medical sciences CD4 Lymphocyte Count CD40 Ligand CD40L Cell Movement Drug Therapy, Combination Fas fas Receptor - analysis Female HIV-1 HIV‐1 infection Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Lymphocyte Activation - drug effects Male Medical sciences Membrane Glycoproteins - analysis Middle Aged Original OX40 Pharmacology. Drug treatments Receptors, OX40 Receptors, Tumor Necrosis Factor T-Lymphocytes - chemistry T-Lymphocytes - physiology Tumor Necrosis Factor Receptor Superfamily, Member 7 - analysis Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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