Anti‐ribosomal antibodies bind the Sm proteins D and B/B

In order to analyse the specificity of human anti‐ribosomal P protein antibodies, anti‐ribosomal P protein antibodies were affinity‐purified from the sera of lupus patients. Their binding capacity towards recombinant SmD protein and recombinant SmB/B′ protein was evaluated by immunoblot and ELISA. E...

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Veröffentlicht in:	Clinical and experimental immunology 1998-04, Vol.112 (1), p.139-143
Hauptverfasser:	CAPONI, L, BOMBARDIERI, S, MIGLIORINI, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody Specificity anti‐P antibodies anti‐ribosomal antibodies anti‐Sm antibodies autoantibodies Autoantibodies - blood Autoantibodies - immunology Autoantigens - genetics Autoantigens - immunology Biological and medical sciences Cross Reactions Enzyme-Linked Immunosorbent Assay Humans Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - immunology Medical sciences Original Protozoan Proteins Receptors, Fc - genetics Receptors, Fc - immunology Recombinant Proteins - genetics Recombinant Proteins - immunology Ribonucleoproteins, Small Nuclear - genetics Ribonucleoproteins, Small Nuclear - immunology Ribosomal Proteins - immunology Ribosomes - immunology Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis snRNP Core Proteins systemic lupus erythematosus
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