Identification and characterization of a DR4‐restricted T cell epitope within chlamydia heat shock protein 60

An epitope within the 60 kD Chlamydia trachomatis heat shock protein (hsp) 60, recognized by a HLA‐DRB1*0401‐restricted T cell clone from a reactive arthritis patient, has been characterized. Stimulatory peptides contained a nine amino acid sequence (residues 38–46) predicted by algorithm to confer...

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Veröffentlicht in:	Clinical and experimental immunology 1997-09, Vol.109 (3), p.439-445
Hauptverfasser:	DEANE, K. H. O., JECOCK, R. M., PEARCE, J. H., GASTON, J. S. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acid Sequence Arthritis, Infectious - immunology Arthritis, Infectious - microbiology Biological and medical sciences Chaperonin 60 - genetics Chaperonin 60 - immunology Chlamydia Infections - immunology Clone Cells Diseases of the osteoarticular system Epitope Mapping Epitopes - genetics Epitopes - immunology Escherichia coli - genetics Escherichia coli - immunology HLA-DR4 Antigen - immunology hsp60 Humans Inflammatory joint diseases Male Medical sciences Molecular Sequence Data Peptides - genetics Peptides - immunology reactive arthritis Recombinant Proteins - immunology Sequence Alignment Sequence Homology, Amino Acid T cell clone T-Lymphocytes - immunology Valine - genetics Valine - immunology
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