Promiscuous mismatch extension by human DNA polymerase lambda

DNA polymerase lambda (Pol λ) is one of several DNA polymerases suggested to participate in base excision repair (BER), in repair of broken DNA ends and in translesion synthesis. It has been proposed that the nature of the DNA intermediates partly determines which polymerase is used for a particular...

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Veröffentlicht in:	Nucleic acids research 2006-01, Vol.34 (11), p.3259-3266
Hauptverfasser:	Picher, Angel J., García-Díaz, Miguel, Bebenek, Katarzyna, Pedersen, Lars C., Kunkel, Thomas A., Blanco, Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Pair Mismatch DNA - biosynthesis DNA Polymerase beta - chemistry DNA Polymerase beta - metabolism DNA-Directed DNA Polymerase - classification Humans Kinetics Oligonucleotides - chemistry Phosphates - chemistry
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