HMDB: the Human Metabolome Database
The Human Metabolome Database (HMDB) is currently the most complete and comprehensive curated collection of human metabolite and human metabolism data in the world. It contains records for more than 2180 endogenous metabolites with information gathered from thousands of books, journal articles and e...
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Veröffentlicht in: | Nucleic acids research 2007-01, Vol.35 (suppl-1), p.D521-D526 |
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creator | Wishart, David S Tzur, Dan Knox, Craig Eisner, Roman Guo, An Chi Young, Nelson Cheng, Dean Jewell, Kevin Arndt, David Sawhney, Summit Fung, Chris Nikolai, Lisa Lewis, Mike Coutouly, Marie-Aude Forsythe, Ian Tang, Peter Shrivastava, Savita Jeroncic, Kevin Stothard, Paul Amegbey, Godwin Block, David Hau, David.D Wagner, James Miniaci, Jessica Clements, Melisa Gebremedhin, Mulu Guo, Natalie Zhang, Ying Duggan, Gavin E MacInnis, Glen D Weljie, Alim M Dowlatabadi, Reza Bamforth, Fiona Clive, Derrick Greiner, Russ Li, Liang Marrie, Tom Sykes, Brian D Vogel, Hans J Querengesser, Lori |
description | The Human Metabolome Database (HMDB) is currently the most complete and comprehensive curated collection of human metabolite and human metabolism data in the world. It contains records for more than 2180 endogenous metabolites with information gathered from thousands of books, journal articles and electronic databases. In addition to its comprehensive literature-derived data, the HMDB also contains an extensive collection of experimental metabolite concentration data compiled from hundreds of mass spectra (MS) and Nuclear Magnetic resonance (NMR) metabolomic analyses performed on urine, blood and cerebrospinal fluid samples. This is further supplemented with thousands of NMR and MS spectra collected on purified, reference metabolites. Each metabolite entry in the HMDB contains an average of 90 separate data fields including a comprehensive compound description, names and synonyms, structural information, physico-chemical data, reference NMR and MS spectra, biofluid concentrations, disease associations, pathway information, enzyme data, gene sequence data, SNP and mutation data as well as extensive links to images, references and other public databases. Extensive searching, relational querying and data browsing tools are also provided. The HMDB is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. The HMDB is available at: www.hmdb.ca |
doi_str_mv | 10.1093/nar/gkl923 |
format | Article |
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Each metabolite entry in the HMDB contains an average of 90 separate data fields including a comprehensive compound description, names and synonyms, structural information, physico-chemical data, reference NMR and MS spectra, biofluid concentrations, disease associations, pathway information, enzyme data, gene sequence data, SNP and mutation data as well as extensive links to images, references and other public databases. Extensive searching, relational querying and data browsing tools are also provided. The HMDB is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. 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It contains records for more than 2180 endogenous metabolites with information gathered from thousands of books, journal articles and electronic databases. In addition to its comprehensive literature-derived data, the HMDB also contains an extensive collection of experimental metabolite concentration data compiled from hundreds of mass spectra (MS) and Nuclear Magnetic resonance (NMR) metabolomic analyses performed on urine, blood and cerebrospinal fluid samples. This is further supplemented with thousands of NMR and MS spectra collected on purified, reference metabolites. Each metabolite entry in the HMDB contains an average of 90 separate data fields including a comprehensive compound description, names and synonyms, structural information, physico-chemical data, reference NMR and MS spectra, biofluid concentrations, disease associations, pathway information, enzyme data, gene sequence data, SNP and mutation data as well as extensive links to images, references and other public databases. Extensive searching, relational querying and data browsing tools are also provided. The HMDB is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. The HMDB is available at: www.hmdb.ca</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>17202168</pmid><doi>10.1093/nar/gkl923</doi><oa>free_for_read</oa></addata></record> |
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subjects | Databases, Factual - standards Humans Internet Mass Spectrometry Metabolic Diseases - genetics Metabolic Diseases - metabolism Metabolic Networks and Pathways Metabolism Nuclear Magnetic Resonance, Biomolecular Quality Control User-Computer Interface |
title | HMDB: the Human Metabolome Database |
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