MYC levels govern hematopoietic tumor type and latency in transgenic mice

Deregulated MYC expression has been implicated in the etiology of many human cancers, including hematopoietic malignancies. To explore the impact of widespread constitutive MYC expression in the hematopoietic compartment, we have used a vector containing regulatory elements of the Vav gene to genera...

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Veröffentlicht in:Blood 2006-07, Vol.108 (2), p.653-661
Hauptverfasser: Smith, Darrin P., Bath, Mary L., Metcalf, Donald, Harris, Alan W., Cory, Suzanne
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Sprache:eng
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