Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34

A broad range of hematopoietic stem cells and progenitors reside within a fraction of umbilical cord blood (UCB) that exhibits low light scatter properties (SSClo) and high expression of aldehyde dehydrogenase (ALDHbr). Many SSClo ALDHbr cells coexpress CD34; however, other cells express either ALDH...

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Veröffentlicht in:	Blood 2005-07, Vol.106 (1), p.95-102
Hauptverfasser:	Storms, Robert W., Green, Patrick D., Safford, Kristine M., Niedzwiecki, Donna, Cogle, Christopher R., Colvin, O. Michael, Chao, Nelson J., Rice, Henry E., Smith, Clayton A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde Dehydrogenase - metabolism Animals Antigens, CD34 - metabolism Biological and medical sciences Biomarkers Cell differentiation, maturation, development, hematopoiesis Cell physiology Cells, Cultured Fetal Blood - cytology Fundamental and applied biological sciences. Psychology Hematopoiesis Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - classification Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - enzymology Humans Killer Cells, Natural - cytology Lymphocytes - cytology Mice Mice, Inbred NOD Mice, SCID Molecular and cellular biology Multipotent Stem Cells - cytology Multipotent Stem Cells - enzymology Myeloid Cells - cytology
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