The αC domains of fibrinogen affect the structure of the fibrin clot, its physical properties, and its susceptibility to fibrinolysis

The functions of the αC domains of fibrinogen in clotting and fibrinolysis, which have long been enigmatic, were determined using recombinant fibrinogen truncated at Aα chain residue 251. Scanning electron microscopy and confocal microscopy revealed that the fibers of α251 clots were thinner and den...

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Veröffentlicht in:	Blood 2005-12, Vol.106 (12), p.3824-3830
Hauptverfasser:	Collet, Jean-Philippe, Moen, Jennifer L., Veklich, Yuri I., Gorkun, Oleg V., Lord, Susan T., Montalescot, Gilles, Weisel, John W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Hemostasis, Thrombosis, and Vascular Biology
Online-Zugang:	Volltext
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