CD4 cells can be more efficient at tumor rejection than CD8 cells

Researchers designing antitumor treatments have long focused on eliciting tumor-specific CD8 cytotoxic T lymphocytes (CTL) because of their potent killing activity and their ability to reject transplanted organs. The resulting treatments, however, have generally been surprisingly poor at inducing co...

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Veröffentlicht in:	Blood 2007-06, Vol.109 (12), p.5346-5354
Hauptverfasser:	Perez-Diez, Ainhoa, Joncker, Nathalie T., Choi, Kyungho, Chan, William F.N., Anderson, Colin C., Lantz, Olivier, Matzinger, Polly
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Histocompatibility Antigens Class I - immunology Histocompatibility Antigens Class II - immunology Immunobiology Immunotherapy Killer Cells, Natural - immunology Mice Mice, Transgenic Neoplasms - immunology T-Lymphocytes, Cytotoxic - immunology
Online-Zugang:	Volltext
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