Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I

Natural killer (NK) cells mediate bone marrow allograft rejection. However, the molecular mechanisms underlying such a rejection remain elusive. In previous analyses, it has been shown that NK cells recognize allogeneic target cells through Ly-49s and CD94/NKG2 heterodimers. Here, we describe identi...

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Veröffentlicht in:	The Journal of experimental medicine 2004-01, Vol.199 (1), p.137-144
Hauptverfasser:	Koike, Junzo, Wakao, Hiroshi, Ishizuka, Yuko, Sato, Taka-aki, Hamaoki, Masaru, Seino, Ken-ichiro, Koseki, Haruhiko, Nakayama, Toshinori, Taniguchi, Masaru
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bone Marrow Transplantation - immunology Brief Definitive Report Gene Library Graft Rejection - immunology Killer Cells, Natural - immunology Mice Mice, Inbred Strains Mice, Nude Molecular Sequence Data NK Cell Lectin-Like Receptor Subfamily K Rats Rats, Inbred F344 Receptors, Immunologic - chemistry Receptors, Immunologic - genetics Receptors, Immunologic - immunology Receptors, Natural Killer Cell T-Lymphocytes - immunology Transplantation, Homologous
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