Presence of immunoreactive corticotropin releasing hormone in thyroid lesions

Corticotropin-releasing hormone (CRH) functions as a regulator of the hypothalamic-pituitary-adrenal axis and coordinator of the stress response. Immunoreactive CRH (IrCRH) is also produced in a variety of inflammatory sites, where this peptide acts as a proinflammatory cytokine. To detect CRH in au...

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Veröffentlicht in:	The American journal of pathology 1994-11, Vol.145 (5), p.1159-1167
Hauptverfasser:	Scopa, CD, Mastorakos, G, Friedman, TC, Melachrinou, M, Merino, MJ, Chrousos, GP
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - isolation & purification Chromatography, High Pressure Liquid Corticotropin-Releasing Hormone - immunology Corticotropin-Releasing Hormone - metabolism Goiter - metabolism Goiter - pathology Humans Immunoenzyme Techniques Rabbits Radioimmunoassay Thyroid Gland - metabolism Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology Thyroiditis, Autoimmune - metabolism Thyroiditis, Autoimmune - pathology
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