PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD68 molecule

A new anti-macrophage monoclonal antibody (PG-M1) was produced by immunizing BALB/c mice with fresh spleen cells from a patient with Gaucher's disease. PG-M1 reacts strongly with a fixative-resistant epitope of an intracytoplasmic molecule, selectively expressed by virtually all macrophages of...

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Veröffentlicht in:	The American journal of pathology 1993-05, Vol.142 (5), p.1359-1372
Hauptverfasser:	Falini, B, Flenghi, L, Pileri, S, Gambacorta, M, Bigerna, B, Durkop, H, Eitelbach, F, Thiele, J, Pacini, R, Cavaliere, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, immunoglobulins Antibodies, Monoclonal - immunology Antibody Formation Antigens, CD - analysis Antigens, CD - immunology Antigens, Differentiation, Myelomonocytic - analysis Antigens, Differentiation, Myelomonocytic - immunology Biological and medical sciences Cell Line DNA - genetics Drug Resistance Epitopes Fixatives - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology Hematologic Diseases - immunology Hematopoietic System Humans Inflammation - immunology Lymphatic Diseases - immunology Macrophages - immunology Molecular immunology Monoclonal antibodies Neoplasms - immunology Precipitin Tests Reference Values Regular Transfection
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