Eosinophils are the major source of transforming growth factor-beta 1 in nodular sclerosing Hodgkin's disease

Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional cytokine which promotes fibroblast growth and collagen synthesis, but suppresses growth and differentiation of immune lymphocytes and killer cells. Immunohistochemical detection of TGF-beta 1 in Hodgkin's disease (HD) has been...

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Veröffentlicht in:The American journal of pathology 1993-01, Vol.142 (1), p.11-16
Hauptverfasser: Kadin, M, Butmarc, J, Elovic, A, Wong, D
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Sprache:eng
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