Interleukin-8. A corneal factor that induces neovascularization

A rabbit corneal pocket model was used to demonstrate that physiologic concentrations of human recombinant (r) IL-8 may induce corneal neovascularization. Computer-assisted analysis of sequential fluorescein angiograms showed that rIL-8 doses ranging from 2 to 40 ng/cornea (P = 0.01), but not high d...

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Veröffentlicht in:	The American journal of pathology 1992-12, Vol.141 (6), p.1279-1284
Hauptverfasser:	Strieter, RM, Kunkel, SL, Elner, VM, Martonyi, CL, Koch, AE, Polverini, PJ, Elner, SG
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiography Animals Biological and medical sciences Cornea - blood supply Cornea - chemistry Diseases of cornea, anterior segment and sclera Eye Proteins - physiology Fluoresceins Image Processing, Computer-Assisted Interleukin-8 - analysis Interleukin-8 - physiology Medical sciences Neovascularization, Pathologic - physiopathology Ophthalmology Rabbits
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