Astrocytic Alterations in Interleukin-6/Soluble Interleukin-6 Receptor α Double-Transgenic Mice

Interleukin-6 (IL-6), a major cytokine with diverse effects on cells mainly of the immune and hematopoietic systems, has been linked to several neurological disorders such as acquired immune deficiency syndrome dementia, multiple sclerosis, and Alzheimer's disease. Central nervous system (CNS)-...

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Veröffentlicht in:	The American journal of pathology 2000-11, Vol.157 (5), p.1485-1493
Hauptverfasser:	Brunello, Anna G., Weissenberger, Jakob, Kappeler, Andreas, Vallan, Claudio, Peters, Malte, Rose-John, Stefan, Weis, Joachim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - pathology Biological and medical sciences Brain - pathology Central Nervous System - pathology Central Nervous System - ultrastructure Gene Expression Humans Interleukin-6 - genetics Interleukin-6 - metabolism Medical sciences Mice Mice, Transgenic - genetics Nervous system involvement in other diseases. Miscellaneous Neurology Phenotype Receptors, Interleukin-6 - genetics Receptors, Interleukin-6 - metabolism Regular Solubility Transgenes - genetics
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