Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma

The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and metastatic capacity of melanoma cells in vitro, but their clinical significance in primary cutaneous melanoma is still unclear. Therefore, we studied whether the levels of CD44 and HA associate with disease progre...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of pathology 2000-09, Vol.157 (3), p.957-965
Hauptverfasser:	Karjalainen, Jari M., Tammi, Raija H., Tammi, Markku I., Eskelinen, Matti J., Ågren, Ulla M., Parkkinen, Jyrki J., Alhava, Esko M., Kosma, Veli-Matti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Dermatology Female Humans Hyaluronan Receptors - metabolism Hyaluronic Acid - metabolism Immunoenzyme Techniques Male Medical sciences Melanoma - metabolism Melanoma - mortality Melanoma - pathology Middle Aged Neoplasm Staging Prognosis Regular Retrospective Studies Skin Neoplasms - metabolism Skin Neoplasms - mortality Skin Neoplasms - pathology Survival Analysis Survival Rate Tumors of the skin and soft tissue. Premalignant lesions
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!