Characterization of a dermal derived malignant mesenchymal tumor arising in ultraviolet irradiated mice

Skh/hr-1 hairless albino mice were irradiated with photocarcinogenic dosages of ultraviolet light for periods of 30 weeks or longer. A high proportion of mice developed pleomorphic spindle cell tumors and epidermal neoplasms of various types. These spindle cell tumors were studied by immunofluoresce...

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Veröffentlicht in:	The American journal of pathology 1989-07, Vol.135 (1), p.149-159
Hauptverfasser:	Phelps, RG, Bernstein, LE, Harpaz, N, Gordon, RE, Cruickshank, FA, Schwartz, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Dermatology Fibrosarcoma - pathology Fibrosarcoma - ultrastructure Immunohistochemistry Medical sciences Mice Mice, Hairless Neoplasms, Radiation-Induced - pathology Neoplasms, Radiation-Induced - ultrastructure Skin Neoplasms - pathology Skin Neoplasms - ultrastructure Tumors of the skin and soft tissue. Premalignant lesions Ultraviolet Rays - adverse effects
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